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miR-511 promotes the proliferation of human hepatoma cells by targeting the 3’UTR of B cell translocation gene 1 (BTG1) mRNA

   
@article{APS9651,
	author = {Shu-qin ZHANG and Zhe YANG and Xiao-li CAI and Man ZHAO and Ming-ming SUN and Jiong LI and Guo-xing FENG and Jin-yan FENG and Li-hong YE and Jun-qi NIU and Xiao-dong ZHANG},
	title = {miR-511 promotes the proliferation of human hepatoma cells by targeting the 3’UTR of B cell translocation gene 1 (BTG1) mRNA},
	journal = {Acta Pharmacologica Sinica},
	volume = {38},
	number = {8},
	year = {2017},
	keywords = {},
	abstract = {Aberrant expression of miR-511 is involved in the development of cancer, but the role of miR-511 in hepatocellular carcinoma (HCC) is not well documented. In this study, we explored the molecular mechanisms of miR-511 in hepatocarcinogenesis. Our results of bioinformatics analysis suggested that B cell translocation gene 1 (BTG1), a member of anti-proliferative gene family, was one of the putative targets of miR-511. The expression levels of miR-511 were significantly higher in 30 clinical HCC tissues than in corresponding peritumor tissues, and were negatively correlated with those of BTG1 in the HCC tissues (r=-0.6105, P},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/9651}
}