@article{APS9130,
author = {Hai Peng and Yue-Fen Li and Sheng-Gang Sun},
title = {Effects of Ginkgo biloba extract on acute cerebral ischemia in rats analyzed by magnetic resonance spectroscopy.},
journal = {Acta Pharmacologica Sinica},
volume = {24},
number = {5},
year = {2016},
keywords = {},
abstract = {AIM: To study the effect of Ginkgo biloba extract (GbE) on acute cerebral ischemia in rats. METHODS: The rats were randomly divided into four groups: sham-operated group (group I as control), ischemic group (group II), the prophylactic (GbE premedication) group (group III) and GbE-treatment group (group IV). Magnetic resonance spectroscopy (MRS) was carried out to dynamically monitor the changes in biochemical metabolic variations 48 h after cerebral ischemia and effects of GbE (100 mg/kg, ip, qd). RESULTS: (1) Lactate (Lac) peak could be detectable at the infarction area 90 min after acute cerebral ischemia and increased with time. Lac peak in the prophylactic group was elevated slightly (P},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/9130}
}