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Reliability of phototoxic tests of fluoroquinolones in vitro.

  
@article{APS9128,
	author = {Ting Zhang and Jun-Ling Li and Xiao-Chao Ma and Jian Xin and Zeng-Hong Tu},
	title = {Reliability of phototoxic tests of fluoroquinolones in vitro.},
	journal = {Acta Pharmacologica Sinica},
	volume = {24},
	number = {5},
	year = {2016},
	keywords = {},
	abstract = {AIM: To make sure the reliability of phototoxic tests in vitro by comparing the phototoxic potential of 4 fluoroquinolones (FQ). METHODS: Lomefloxacin (LFLX), sparfloxacin (SPFX), ciprofloxacin (CPFX), and norfloxacin (NFLX) were tested by Wistar rat phototoxic test and Balb/c mouse phototoxic test in vivo, and Chinese hamster V79 cell micronucleus test and NIH 3T3 MTT test in vitro under the different condition of UVA irradiation. RESULTS: In all experiments, LFLX and SPFX showed higher phototoxic potential compared with the control (P},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/9128}
}