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Effects of phenothiazine drugs on serum levels of apolipoproteins and lipoproteins in schizophrenic subjects

   
@article{APS9059,
	author = {Fang Wen and Jie Tan},
	title = {Effects of phenothiazine drugs on serum levels of apolipoproteins and lipoproteins in schizophrenic subjects},
	journal = {Acta Pharmacologica Sinica},
	volume = {24},
	number = {10},
	year = {2016},
	keywords = {},
	abstract = {AIM: To investigate the risk factors and clinical significance of blood-lipid metabolic disorder in schizophrenic patients caused by phenothiazine treatment for long term (from 1 month to 25 years). 
METHODS: Serum levels of apolipoprotein AI (apoAI), apolipoprotein B (apoB), high-density lipoprotein cholesterol (HDL-C), triglyceride (TG), and total cholesterol (TC) were measured in 120 chronic schizophrenia patients, 50 vascular dementia, and 100 normal controls by the enzyme method and immune fluoroscopy turbidimetric method. 
RESULTS: The patients with schizophrenia and vascular dementia had significantly lower content of apoAI, HDL-C, and apoAI/apoB than those in normal control (P},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/9059}
}