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Ginkgo biloba leaf extract enhances levels of caspase-3 and amyloid precursor protein in normal rat hippocampus.

   
@article{APS9050,
	author = {Can Luo and Qin Wu and Xie-Nan Huang and An-Sheng Sun and Jing-Shan Shi},
	title = {Ginkgo biloba leaf extract enhances levels of caspase-3 and amyloid precursor protein in normal rat hippocampus.},
	journal = {Acta Pharmacologica Sinica},
	volume = {24},
	number = {2},
	year = {2016},
	keywords = {},
	abstract = {AIM: To explore the effect of Ginkgo biloba extract (GbE) on the levels of caspase-3 and amyloid precursor protein (APP) in normal rats' hippocampus. METHODS: Immunohistochemistry method was used for qualitative analysis of the expressions of caspase-3 and APP, and an image analysis method was used for the quantification of the levels of caspase-3 and APP after GbE was administered to rats of different ages for 14 d. RESULTS: The mean absorbance of staining of caspase-3 and APP was markedly higher in GbE group than that in control groups. The expressions of caspase-3 and APP were intensified in the hippocampus of rats after GbE administration. CONCLUSION: GbE can raise the levels of caspase-3 and APP in the hippocampus of normal rats.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/9050}
}