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Resveratrol inhibits matrix metalloproteinase-9 transcription in U937 cells

   
@article{APS9043,
	author = {Yi-Tang Li and Fang Shen and Bai-He Liu and Gui-Fang Cheng},
	title = {Resveratrol inhibits matrix metalloproteinase-9 transcription in U937 cells},
	journal = {Acta Pharmacologica Sinica},
	volume = {24},
	number = {11},
	year = {2016},
	keywords = {},
	abstract = {AIM: To examine the inhibitory effect of resveratrol on matrix metalloroteinase-9 (MMP-9) and explore its mechanism. 
METHODS: MMP-9 activity was analyzed by gelatin zymography; MMP-9 protein was detected by Western blot; MMP-9 mRNA expression was investigated by RT-PCR. Activation of activator protein -1 (AP-1) was measured by electrophoretic mobility shift assay (EMSA). 
RESULTS: MMP-9 activity in U937 cells increased significantly after exposed to PMA at 10 nmol/L for 24 h without FCS (P},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/9043}
}