@article{APS9022,
author = {Ben-Xiang Wang and Qiu-Li Zhou and Ming Yang and Yan Wang and Zhi-Yong Cui and Yong-Qiang Liu and Takashi Ikejima},
title = {Hypoglycemic activity of ginseng glycopeptide.},
journal = {Acta Pharmacologica Sinica},
volume = {24},
number = {1},
year = {2016},
keywords = {},
abstract = {AIM: To study the hypoglycemic activity of ginseng glycopeptide (GGP). METHODS: Normal mice or rabbits and alloxan or streptozotocin-induced hyperglycemic rats or mice were used in the study. Blood glucose and liver glycogen levels of the experimental animals during the trial period were analyzed by spectrophotometry with O-toluidine and iodine reagents, respectively. RESULTS: Significant decreases in blood glucose and liver glycogen levels were induced in a dose-dependent manner after administration of GGP 50, 100, or 200 mg/kg injected ip or sc to normal mice and injected im 30 or 60 mg/kg to normal rabbits. The hypoglycemic activity of GGP lasted for about 16 h, and were examined in both normal animals and hyperglycemic animals. CONCLUSION: GGP injection induced the pronounced decreases in blood glucose and liver glycogen levels in both normal and hyperglycemic animals.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/9022}
}