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Relationship between cardiotonic effects and inhibition on cardiac sarcolemmal Na+,K+-ATPase of strophan-thidin at low concentrations

   
@article{APS9020,
	author = {Su-Wen Su and Yong-Li Wang and Jun-Xia Li and He-Shan Mei and Jing-Xiang Yin},
	title = {Relationship between cardiotonic effects and inhibition on cardiac sarcolemmal Na+,K+-ATPase of strophan-thidin at low concentrations},
	journal = {Acta Pharmacologica Sinica},
	volume = {24},
	number = {11},
	year = {2016},
	keywords = {},
	abstract = {AIM: To evaluate the effects of strophanthidin (Str) on cardiac contractile function and sarcolemmal Na+, K+-ATPase activities in isolated guinea-pig hearts. 
METHODS: Isolated guinea-pig hearts were perfused through aorta in a Langendorff mode. Heart rate (HR), left ventricular pressure (LVP), and first derivatives (+/-dp/dt(max)) of LVP were recorded by eight-channel physiological instrument. Cardiac sarcolemmal Na+, K+-ATPase activities were determined with colorimetry. 
RESULTS: Str 0.1 nmol/L stimulated the Na+, K+-ATPase activities (P},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/9020}
}