@article{APS8791,
author = {Xiu-Ling Deng and Pei-Lun Qiu and Jun-Tian Liu and Shu-Ying Chen},
title = {Protective effects of 3, 6-dimethamidodibenzopyriodinium citrate on myocardial injury induced by ischemia and reperfusion in rats},
journal = {Acta Pharmacologica Sinica},
volume = {14},
number = {4},
year = {2016},
keywords = {},
abstract = {3, 6-Dimethamidodibenzopyriodonium citrate (I-65) 0.5 and 1 mg.kg-1 pretreatment reduced the size of myocardial infarct after ischemia for 40 min and reperfusion for 120 min. I-65 0.5 mg.kg-1 decreased myocardial creatine kinase, lactate dehydrogenase release, and Ca2+ accumulation after ischemia for 40 min and reperfusion for 120 min. The results show that I-65 prevents cardiac ischemia and reperfusion injury and the effect is considered to be related to inhibition of myocardial Ca2+ accumulation.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/8791}
}