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Pharmacokinetics and relative bioavailability of nimodipine capsules and tablets in 8 Chinese healthy men

   
@article{APS8771,
	author = {Lian-Qing Guo and Heng-Shan Tan and Gang Chen},
	title = {Pharmacokinetics and relative bioavailability of nimodipine capsules and tablets in 8 Chinese healthy men},
	journal = {Acta Pharmacologica Sinica},
	volume = {14},
	number = {4},
	year = {2016},
	keywords = {},
	abstract = {A single oral dose of tablets or capsules of 239 mumol nimodipine was given to 8 healthy volunteers of Han nationality in a randomized crossover study. Plasma levels were determined with HPLC method. The plasma concentration-time curve fitted to a first order absorption, 1-compartment open model, and the T1/2K was around 2 h. Although the capsules could reach peak level faster, the bioavailability was not significantly different from that of the tablets.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/8771}
}