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Contents of endogenous phencyclidine-like substances in cerebrospinal fluid of schizophrenic patients

   
@article{APS8687,
	author = {Guang-Zhao Zhou and Da-Wei Gong and Ming-Kang Lu and Liang-Dong Zhang and Jing-Li Yao and Han-Qian Lu-fei and Hui Gao and An-Zhong Zhang},
	title = {Contents of endogenous phencyclidine-like substances in cerebrospinal fluid of schizophrenic patients},
	journal = {Acta Pharmacologica Sinica},
	volume = {9},
	number = {6},
	year = {2016},
	keywords = {},
	abstract = {The contents of endogenous phencyclidine-like substances (EPS) in the cerebrospinal fluid (CSF) of schizophrenic and ataxic patients were measured by a radioligand assay. The CSF of 10 schizophrenic patients and 10 non-schizophrenic patients  (control group) suffering from peripheral  neuritis. myelopathy. muscleatrophy of the limbs and serious migraines were run through a Sephadex G-25 fine column. Fractions 17-19 were pooled and lyophilized for radioligaid assayirg.  The results showed that the average content of EPS in CSF of schizophrenic patients was 187 pmol/ml CSF,  avalue, Nhich was lower than that of the control group (492 pmol/ml CSF. p},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/8687}
}