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Clonidine inhibition effect on synaptic transmission of guinea pig celiac ganglia

  
@article{APS8654,
	author = {Qing-Lan Shao and Lin Ou and Zhen-Xin Huang and Rui-Ling Wu and Ru-Chun Ma},
	title = {Clonidine inhibition effect on synaptic transmission of guinea pig celiac ganglia},
	journal = {Acta Pharmacologica Sinica},
	volume = {9},
	number = {5},
	year = {2016},
	keywords = {},
	abstract = {After superfusion of the celiac ganglia  with  clonidine  (0.01-10 vmol/L). the N type-cholinergic transmission was reversibly depressed. This effect was blocked by  yohimbine  (10 vmol/L),  but  was  not affected by prazosin (10 vmol/L) and propranolol (10 vmol/L) respectively.  It is indicated that clonidine inhibition effect on synaptic transmission is mediated by a2-adrenoceptors. Since ACh potentials decreased when synaptic transmission was depressed by clonidine, clonidine inhibition effect on synaptic transmission is partially related to post-synaptic mechanism.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/8654}
}