How to cite item

Experimental therapy of 7 antimalarials in mice infected with pyronaridine-resistant berghei

   
@article{APS8547,
	author = {Ke-yong Chen and Bao-ying Lin and Jia-xun Zhang and Bao-ruo Shao},
	title = {Experimental therapy of 7 antimalarials in mice infected  with pyronaridine-resistant berghei},
	journal = {Acta Pharmacologica Sinica},
	volume = {4},
	number = {4},
	year = {2016},
	keywords = {},
	abstract = {Seven antimalarials were used in treating mice infected with plaswtodiuwt berghei or pyronaridine-resistant(RP)line of p. berghei.The result showed that RP line was cross-resistant to chloroquine, piperaquine, quinine and quinacrine but susceptible to pyrimethamine and sulfadoxine. The ED50 of pyrimethamine and sulfadoxine were 52.2 and 0.67 mg/kg/d x3, respectively. Artemisinine was effective to RP line at a higher dosage. and its ED50 was  1034 mg/kg/d x 3. pyrimethamine in combination with sulfadoxine resulted in a potentiating effect against pyronaridine-resistant line of p.berghei.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/8547}
}