@article{APS8540,
author = {Feng-zhen Tang and Ji-an Guo and Wei-guang Zhao and Shu-yuan Tang and Yong-jun Xie and Gui-min Li},
title = {Anti-arrhythmic eefects of sodiijm selenite},
journal = {Acta Pharmacologica Sinica},
volume = {4},
number = {4},
year = {2016},
keywords = {},
abstract = {The effects of Na2Se03 on aconitinc- ouabain-, BaCl2- and chloroform-induced arrhythmias were studied. Na2Se03 2 mg/kg iv elevated the threshold doses of ouabain necessary to induce ventricular premature beats in guinea pigs but had no protective effects on aconitine- or BaC12-induced arrhythmias in rats. After ip l mg/kg/d x 5 d the threshold doses of aconitine, ouabain and BaC12 to induce various kincls of arrhythmias and heart arrest were increaseci. Na2SeO3 did not influence the chloroform-induced arrhythmia in mice. The effect of multiple doses of Na2SeO3 on ouabain-arrhythmias seems to resemble that of lidocaine.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/8540}
}