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Some pharmacological actions of ginseng saponins

  
@article{APS8506,
	author = {Wen-xue Yuan and Lu-he Gui and Jian-ying Zhou and Qi-yun Li and Qing-hai Yu},
	title = {Some pharmacological actions of ginseng saponins},
	journal = {Acta Pharmacologica Sinica},
	volume = {4},
	number = {2},
	year = {2016},
	keywords = {},
	abstract = {Ginseng saponins (GS) inhi-bited the  croton oil-induced edema in mouse ear and the carrageenan-induced edema in  rat hind  paw, when  GS  were injected ip 160 mg/kg. In mice ip GS 130 or 266 mg kg produced an antidiuretic effect, ip 160 mg/kg prolonged  the  sleeping time of sodium pentobarbital, and ip 50 and 180 mg/kg potentiated the insulin shock. GS caused a stimulation, followed by an inhi-bition, on isolated heart at 0.18, 0.36, 0.72 mg/ml,  and  an  inhibition at l.44 mg/ml. On isolated intestine GS 0.05, 0.09, 0.14, 0.19 mg/ml yielded a dose-dependent inhibition.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/8506}
}