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Homocysteine induces production of monocyte chemoattractant protein-1 and interleukin-8 in cultured human whole blood

  
@article{APS8401,
	author = {Xiao-kun ZENG and Daniel G REMICK and Xian WANG},
	title = {Homocysteine induces production of monocyte chemoattractant protein-1 and interleukin-8 in cultured human whole blood},
	journal = {Acta Pharmacologica Sinica},
	volume = {25},
	number = {11},
	year = {2016},
	keywords = {},
	abstract = {AIM:
To investigate whether increased plasma L-homocysteine (Hcy) level could promote monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) in cultured whole blood.
METHODS:
Human whole blood or different type of peripheral blood cells from health volunteers were incubated with Hcy and/or the inhibitors. MCP-1 and IL-8 level were measured by ELISA assay.
RESULTS:
Hcy 10-1000 micromol/L induced production of MCP-1 and IL-8 in cultured human whole blood (P},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/8401}
}