@article{APS8196,
author = {Guang-he FEI and Rong-yu LIU and Zhi-hong ZHANG and Jiang-ning ZHOU},
title = {Alterations in circadian rhythms of melatonin and cortisol in patients with bronchial asthma},
journal = {Acta Pharmacologica Sinica},
volume = {25},
number = {5},
year = {2016},
keywords = {},
abstract = {AIM:
To investigate the possible relationships between alterations in circadian rhythm of melatonin, cortisol and bronchial asthma.
METHODS:
Salivary melatonin and cortisol were measured simultaneously by radioimmunoassay in 10 mild intermittent or persistent patients, 11 moderate-to-severe persistent asthma patients, and 15 control subjects. Twelve salivary samples were collected in a series during a 24-h period in each subject.
RESULTS:
The results showed overall lower levels of salivary melatonin in asthma patients compared with control subject (P},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/8196}
}