How to cite item

Long-term potentiation induced by nicotine in CA1 region of hippocampal slice is Ca(2+)-dependent

   
@article{APS8020,
	author = {Jin He and Chun-Yu Deng and Ru-Zhu Chen and Xiao-Nan Zhu and Jian-Ping Yu},
	title = {Long-term potentiation induced by nicotine in CA1 region of hippocampal slice is Ca(2+)-dependent},
	journal = {Acta Pharmacologica Sinica},
	volume = {21},
	number = {5},
	year = {2016},
	keywords = {},
	abstract = {\"AIM:
To observe the effects of Ca2+ on hippocampal long-term potentiation (LTP) induced by nicotine in CA1 region of rat hippocampal slice.
METHODS:
Extracellularly recorded population spikes (PS) of the pyramidal cell layer in the hippocampal CA1 region in vitro.
RESULTS:
Nicotine 1 mumol.L-1 induced LTP in the hippocampal CA1 region. It did not induce LTP in CA1 region when CA2+ was removed from artificial cerebrospinal fluid (ACSF). Nifedipine 1 and 10 mumol.L-1 partly inhibited LTP induced by nicotine, and thapsigargin 1 and 10 mumol.L-1 completely inhibited LTP induced by nicotine.
CONCLUSION:
LTP induced by nicotine in hippocampal CA1 region is Ca(2+)-dependent. Both Ca2+ influx and Ca2+ release participate in the induction of LTP.\"},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/8020}
}