@article{APS7696,
author = {Yang LI and Lo-Ying FU and Wei-Xing YAO and Guo-Jin XIA and Ming-Xing JIANG},
title = {Effects of benzyltetrahydropalmatine on potassium currents in guinea pig and rat ventricular myocytes.},
journal = {Acta Pharmacologica Sinica},
volume = {23},
number = {7},
year = {2016},
keywords = {},
abstract = {AIM: To investigate the effects of benzyltetrahydropalmatine (BTHP) on rapidly
activating component (I(Kr)), slowly activating component (I(Ks)) of delayed
rectifier potassium current, inward rectifier potassium current (I(K1)), and
transient outward potassium current (I(to)) in single ventricular myocytes.
METHODS: Whole-cell patch clamp technique was used to record ionic currents.
RESULTS: (1) BTHP 30 micromol/L reduced I(Kr) and I(Kr,tail) by 31 %+/-4 % and 36
%+/-5 % (n=6, P },
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/7696}
}