@article{APS7571,
author = {Quan ZHOU and Tong-Wei YAO and Su ZENG},
title = {Effects of stereochemical aspects on drug interaction in pharmacokinetics.},
journal = {Acta Pharmacologica Sinica},
volume = {23},
number = {5},
year = {2016},
keywords = {},
abstract = {Recent literatures on enantiomer/enantiomer and enantiomer/coadministered drug
interactions in pharmacokinetics were reviewed. The clinical significance of
introducing the concept of stereoselectivity into pharmacokinetic interaction
study cannot be overestimated, such as avoiding interaction-based adverse
reactions, increasing therapeutic index, resolving the apparent anomaly in the
plasma concentration-effect relationship and providing starting point of
investigation into drug disposition, etc. Study in this respect should be
enhanced.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/7571}
}