@article{APS7308,
author = {Xia Zhong and Hai-yang Zhang and Hui Tan and Yi Zhou and Fu-li Liu and Fu-qin Chen and De-ya Shang},
title = {Association of serum omentin-1 levels with coronary artery disease},
journal = {Acta Pharmacologica Sinica},
volume = {32},
number = {7},
year = {2016},
keywords = {},
abstract = {Aim: Omentin-1, a novel adipokine expressed in visceral adipose tissue, is negatively correlated with insulin resistance and obesity. Decreased omentin-1 expression has been found in many chronic inflammatory diseases. However, the role of omentin-1 in coronary artery disease (CAD) has not been elucidated. The aim of the present study was to determine whether serum concentration of omentin-1 was independently associated with CAD.
Methods: One hundred and fifty five patients with CAD were divided into two groups: acute coronary syndrome (ACS) and stable angina pectoris (SAP). A total of 52 healthy participants served as controls. Serum concentrations of omentin-1 and interleukin-6 (IL-6) were measured using ELISA. The association of omentin-1 with CAD and cardiovascular disease risk factors was evaluated.
Results: Serum omentin-1 levels were lower in patients with ACS or SAP compared with controls (ACS, 113.08±61.43 ng/mL; SAP, 155.41±66.89 ng/mL; control, 254.00±72.9 ng/mL; P},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/7308}
}