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Huperzine A (shuangyiping): a promising drug for Alzheimer's disease

   
@article{APS7095,
	author = {Xi-Can Tang},
	title = {Huperzine A (shuangyiping): a promising drug for Alzheimer's disease},
	journal = {Acta Pharmacologica Sinica},
	volume = {17},
	number = {6},
	year = {2016},
	keywords = {},
	abstract = {Hup A, a novel alkaloid isolated from Chineses herb Huperzia serrata, is a potent and selective inhibitor of AChE, with a rapid absorption and penetration into the brain in experimental animals. The inhibition is reversible with a longer duration of action. Hup A exhibited memory-enhancing activities in a broad range of animal cognitive model. Compared to Phy, Tac, and Gal, Hup A has better therapeutic indices, and peripheral cholinergic side effects are minimal at therapeutic doses. These findings suggest that Hup A is a promising candidate for clinical development as a symptomatic treatment for AD.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/7095}
}