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Point-of-care test of heart-type fatty acid-binding protein for the diagnosis of early acute myocardial infarction

  
@article{APS6636,
	author = {Chun-jian Li and Jie-qi Li and Xiao-fang Liang and Xiao-xiang Li and Jian-guo Cui and Zhi-jian Yang and Qing Guo and Ke-jiang Cao and Jun Huang},
	title = {Point-of-care test of heart-type fatty acid-binding protein for the diagnosis of early acute myocardial infarction},
	journal = {Acta Pharmacologica Sinica},
	volume = {31},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {Aim:  To investigate the efficacies of point-of-care test of heart-type fatty-acid binding protein (H-FABP) and its combinations with the conventional biomarkers in the diagnosis of early acute myocardial infarction (AMI).
Methods:  227 patients suspected of AMI were consecutively recruited in two centers. Biomarkers including H-FABP, myoglobin (MYO), creatine kinase-myocardial band (CK-MB) and cardiac troponin T (cTnT) were determined simultaneously at admission. AMI was defined according to the universal definition of myocardial infarction. Chi-Square test was adopted for the analysis.
Results:  In patients presenting within 12 h of symptom onset, the sensitivity of H-FABP[93.0% (95% CI: 86.6%−96.9%)] was significantly higher than that of initial CK-MB [67.5% (95% CI: 58.1%−76.0%),P},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/6636}
}