%0 Journal Article
%T Effects of melitten on isolated rat atrium
%A You Yu-Hong
%A Huang Zi-Qiang
%A Li Chang-Chun
%J Acta Pharmacologica Sinica
%D 2016
%B 2016
%9 
%! Effects of melitten on isolated rat atrium
%K 
%X AIM :To8tudYtheefectsofmeliten(Md)onrat heart.   METHODS: The isolated rat atria were adopted. Before and after giving M el, t}le heart rate,contraction ofatrium,post-restomataretion and staircase were m easured.   RESULTS: Verapamil(V日 ) 0.1 ~tmol·L-1 was found to inhibit heart rate in the right atria of rats increased by M el20.0 mg·L~ . Inldtatriaofrats,the D0s£-rest o~ntracfon wa3 jnKbited na d typical positive staircase was markedly at tenuated by Md 2.5 m g ‘L~ . Md possessed negative inotropie elfecur on both t}le left na d right atria of rats.   CONCLUSION: Md posesed negative inotropie and positive chronotropicactionson rat heart.
%U http://www.chinaphar.com/article/view/6542
%V 18
%N 1
%P 87-89
%@ 1745-7254