@article{APS6542,
author = {Yu-Hong You and Zi-Qiang Huang and Chang-Chun Li},
title = {Effects of melitten on isolated rat atrium},
journal = {Acta Pharmacologica Sinica},
volume = {18},
number = {1},
year = {2016},
keywords = {},
abstract = {AIM :To8tudYtheefectsofmeliten(Md)onrat heart.
METHODS: The isolated rat atria were adopted. Before and after giving M el, t\}le heart rate,contraction ofatrium,post-restomataretion and staircase were m easured.
RESULTS: Verapamil(V日 ) 0.1 ~tmol·L-1 was found to inhibit heart rate in the right atria of rats increased by M el20.0 mg·L~ . Inldtatriaofrats,the D0s£-rest o~ntracfon wa3 jnKbited na d typical positive staircase was markedly at tenuated by Md 2.5 m g ‘L~ . Md possessed negative inotropie elfecur on both t\}le left na d right atria of rats.
CONCLUSION: Md posesed negative inotropie and positive chronotropicactionson rat heart.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/6542}
}