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Lithium-induced norepinephrine release from hippocampal slices in the absence of extracellular Ca2+

   
@article{APS6367,
	author = {Hua-yu Huang and Pei-guo Xie and Yi-zheng Huang},
	title = {Lithium-induced norepinephrine release from hippocampal slices in the absence of extracellular Ca2+},
	journal = {Acta Pharmacologica Sinica},
	volume = {15},
	number = {4},
	year = {2016},
	keywords = {},
	abstract = {Slices of rat hippocampus, preincubated with [3H] norepinephrine ([3H]NE) were superfused with Ca(2+)-free medium containing desipramine 1 mumol.L-1, Li+ (40-80 mmol.L-1) evoked [3H]NE release in a concentration dependent manner. It was enhanced by 4 beta-phorbol 12,13-dibutyrate (PDB) and inhibited by tetrodotoxin. Ca(2+)-chelator BAPTA-AM did not attenuate this Li-evoked [3H]NE release. After application of 3,4-diaminopyridine to evoke [3H]NE release and PDB to enhance this release, the Li(+)-evoked [3H]NE release was significantly inhibited. The findings suggest that the liberation of internal Ca2+ stores was not involved in this release process.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/6367}
}