How to cite item

Epitopes recognized by anti-reduced and alkylated acetylcholinesterase antibodies

   
@article{APS6289,
	author = {Yu-xia Wang and Yan-bin Xin and Man-ji Sun},
	title = {Epitopes recognized by anti-reduced and alkylated acetylcholinesterase antibodies},
	journal = {Acta Pharmacologica Sinica},
	volume = {15},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {Peptides of the reduced and alkylated acetylcholinesterase (RA-AChE) from the electric organ of Torpediniformes Torpedo torpedo subjected to bromo-cynogen (CNBr) cleavage or/and peptic digestion conserved well the antigen-antibody reactivity with anti-RA-AChE monoclonal antibodies E9, F6, and F12, whereas peptides produced by CNBr and tryptic treatments lost all the reactivity. Periodate oxidation of the RA-AChE or glycopeptidase digestion of the CNBr cleaved RA-AChE did not change the antigen-antibody reactivity. It implied that the epitopes recognized by the 3 anti-RA-AChE monoclonal antibodies are all peptide determinants rather than carbohydrate determinants},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/6289}
}