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Effects of clonidine on experimental stomach ulcer in rats

  
@article{APS5754,
	author = {Guan-yi LUO and Yun HE and Ling-bo TU},
	title = {Effects of clonidine on experimental stomach ulcer in rats},
	journal = {Acta Pharmacologica Sinica},
	volume = {11},
	number = {5},
	year = {2016},
	keywords = {},
	abstract = {Clonidine 2 mg/kg ig inhibited the rat gastric ulcers induced by pyloric ligation, stress and indomethacin by 71%, 77% and 82%, respectively. Clonidine 2 mg/kg ig tended to accelerate the healing of gastric ulcer induced by acetic acid, and the healing rate was 61%. Clonidine decreased the secretion of gastric acid and pepsin, and increased the release of gastric barrier mucus. These actions may contribute to its protective effect against ulceration.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/5754}
}