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Effects of Tremella polysaccharides on immune function in mice

  
@article{APS5599,
	author = {Dong Xia and Zhi-bin Lin},
	title = {Effects of Tremella polysaccharides on immune function in mice},
	journal = {Acta Pharmacologica Sinica},
	volume = {10},
	number = {5},
	year = {2016},
	keywords = {},
	abstract = {It was found in vitro that Tremella polysaccharides (TP) (50, 100, 150 and 200 micrograms/ml) augmented lymphocyte proliferation induced by Con A and did not antagonize the suppressive effect of hydrocortisone on lymphocyte proliferation. In vivo TP promoted the plaque-forming cell (PFC) response to SRBC in mice. TP 50 and 100 mg/kg ip for 5 d produced 77.6% and 81.8% increases in PFC response respectively. At the doses of 150 and 200 micrograms/ml, TP decreased the interleukin 2 (IL-2) activities in the supernatant of culture media of mouse spleen cells. TP (50 micrograms/ml) enhanced the lymphocyte proliferation induced by Con A and increased the PFC response to SRBC by 47.1% in 14-month-old mice.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/5599}
}