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Effects of sodium molybdate on guinea pig atria contractility

   
@article{APS5489,
	author = {Xin MA and Xiao-guang LI},
	title = {Effects of sodium molybdate on guinea pig atria contractility},
	journal = {Acta Pharmacologica Sinica},
	volume = {11},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {Sodium molybdate (Mo) 10-1000 mumol/L markedly reduced the contratile force of left atria isolated from guinea pig. Mo 100 mumol/L obviously reduced the heart rates in right atria, markedly prolonged the functional refractory period from 185 +/- 12 to 245 +/- 4 ms and inhibited the resting potentiation. Mo 100 and 300 mumol/L reduced the frequency-dependent positive staircase phenomenon. However, verapamil 25 mumol/L reversed the frequency-dependent positive staircase phenomenon to negative one. The mechanism can be explained by the effect on Ca2+ movement in the heart atrium.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/5489}
}