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Effects of nicardipine on beating rates of cultured myocardial cells

  
@article{APS5425,
	author = {Jia-cui YANG and Chuan-lin YU},
	title = {Effects of nicardipine on beating rates of cultured myocardial cells},
	journal = {Acta Pharmacologica Sinica},
	volume = {11},
	number = {2},
	year = {2016},
	keywords = {},
	abstract = {Nicardipine (Nic) 15 nmol/L had no effects on beating rates of cultured myocardial cells. Nic 75 and 150 nmol/L depressed the beating rates significantly. Rapid standstills occurred earlier and more in 150 nmol/L group than in 75 nmol/L. Both isoproterenol and CaCl2 restored the beating depressed by Nic. However, only CaCl2 prevented the standstill. These results suggest that nicardipine may compete with calcium in excitation-contraction coupling.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/5425}
}