@article{APS5406,
author = {Tong-jun ZHU and Xing-yan CHEN and Jian-chun PAN and Shi-shan ZHANG},
title = {Antagonism of Zn2+ on nootropic action of piracetam in mice},
journal = {Acta Pharmacologica Sinica},
volume = {11},
number = {2},
year = {2016},
keywords = {},
abstract = {In mouse step-down test, the memory impairments of acquisition, consolidation and recognition were induced by anisodine, chloramphenical and ethanol, respectively. Piracetam 100 mg/(kg.d) ip for 5 d improved the anisodine-induced impairment of learning. ZnSO4 5 mg/(kg.d) po for 5 d did not improve the 3 impairments. Memory impairments were enhanced by a combined administration of ZnSO4 and piracetam in these 3 models. These results were confirmed by Y-maze method in normal mice.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/5406}
}