TY - JOUR AU - Xie Xi-tao AU - Liu Qiang AU - Wu Jie AU - Wakui Makoto PY - 2016 TI - Impact of cigarette smoking in type 2 diabetes development JF - Acta Pharmacologica Sinica; Vol 30, No 6 (June 2009): Acta Pharmacologica Sinica(Special Feature:Nicotinic Receptors and Nicotine Addiction) Y2 - 2016 KW - N2 - Many patients with type 2 diabetes mellitus (DM2) are at risk for micro and macro vascular complications, which could be observed in heavy smokers. Cigarette smoking increases the risk for type 2 diabetes incidence. Nicotine, acknowledged as the major pharmacologically active chemical in tobacco, is responsible for the association between cigarette smoking and development of diabetes. This minireview summarized recent studies on nicotine effects on insulin action and insulin secretion, indicating the impact of nicotine on type 2 diabetes development. UR - http://www.chinaphar.com/article/view/5220