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Effects of anticonvulsants on cyclic nucleotide contents in plasma and cerebellum of convulsive rats

   
@article{APS5022,
	author = {Zi-Hui Jiang and Gui-Fang Cheng and Jia Chen and Li-Ping Wang and Ting-Chong Zhou},
	title = {Effects of anticonvulsants on cyclic nucleotide contents in plasma and cerebellum of convulsive rats},
	journal = {Acta Pharmacologica Sinica},
	volume = {8},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {With radioimmunoassay of cyclic GMP and protein binding radiometric assay of cyclic AMP we studied the effects of clonazepam, diazepam and scopolamine on cyclic nucleotide contents in plasma and cerebellum of convulsive rats. Bicyclic phosphoester and soman induced convulsion in rats. Both bicyclic phosphoester (0.26μmol /kg ip) and soman (0.49μmol/kg sc) caused the increase of cerebellar cyclic GMP from 4.0±1.1 to 30±5 pmol/mg protein, p},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/5022}
}