@article{APS5018,
author = {De-lin WU and Li-min ZHANG and Jie SUN and Qi CHEN and Nai-bou WU and Zheng-feng GAO and Qing-wu MAO},
title = {Absorption and distribution of 125I-modified snake neurotoxin in rats},
journal = {Acta Pharmacologica Sinica},
volume = {7},
number = {4},
year = {2016},
keywords = {},
abstract = {Rats were injected iv or im with 1.18 MBq of 125I-modified snake neurotoxin (125I-MN) in 0.4 ml saline. The radioactivity in blood rapidly decreased at 1-30 min after iv, but elevated rapidly after im. 125I-MN reached the peak concentration in blood at 30 min. The rate of elimination was 8.2% at 30 min. The biological t1/2 was 8.5 h in blood with a bioavailability of 52% after im. The order of radioactivities in various organs: kidney>lung>hypophysis>liver>adrenals>diaphragm>spleen},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/5018}
}