How to cite item

Pharmacodynamics of 5-(1,3,3-trimethylindolinyl) N, N-dimethyl carbamate in mice

  
@article{APS5017,
	author = {Jie-fu JIN and Ru-heng HUANG},
	title = {Pharmacodynamics of 5-(1,3,3-trimethylindolinyl) N, N-dimethyl carbamate in mice},
	journal = {Acta Pharmacologica Sinica},
	volume = {7},
	number = {4},
	year = {2016},
	keywords = {},
	abstract = {5-(1,3,3-Trimethylindolinyl) N, N-dimethyl carbamate (TMDMC) is a strong cholinesterase inhibitor. The concentration (C) in blood of mice was measured after ip TMDMC 1.5 mg/kg and the % inhibition of blood and brain cholinesterases were calculated by following equations:
Ln[Eblood/(100-Eblood)]=3.58+/-0.9941 ln Cblood
Ln[Ebrain/(100-Ebrain)]=1.91+/-ln Cblood
The inhibition of brain cholinesterase was estimated by the following equation from the degree of blood cholinesterase inhibited.
ln Ebrain=3.67 Eblood+3.69
Measuring the extent of miosis (M) of mice following in TMDMC 1.0, 0.5, 0.25 mg/kg the blood concentration (C) was calculated by the equation:
Ln (M/(100-M))=3.65+1.006 ln C},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/5017}
}