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Effects of ascorbic acid on electric activities of Purkinje fibers

   
@article{APS4933,
	author = {Xiao-guang Li and Lin Yang and Xiao-jiang Yu and Geng-sheng Zhao},
	title = {Effects of ascorbic acid on electric activities of Purkinje fibers},
	journal = {Acta Pharmacologica Sinica},
	volume = {6},
	number = {4},
	year = {2016},
	keywords = {},
	abstract = {The Purkinje fiber action potential of pigs was recorded with microelectrode technique in vitro. Ascorbic acid (AA) 5.7 mmol/L remarkably lengthened APD90, but its effects on APH, Vmax, ERP and APD 50 were not significant. AA 34 mmol/L lengthened APD50 and APD90 evidently and the effective refractory period tended to elongate, but had no evident effect on APH and Vmax. These results suggest that the  antiarrhythmic effect of AA may be related to the APD prolongation.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/4933}
}