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Circadian effect on gastrodin pharmacokinetics in rats

  
@article{APS4920,
	author = {Chang-wei LU and Yuan-jie ZOU and Qi-zhong MO and Jian HUANG and De-quan CHU and De-yong YE},
	title = {Circadian effect on gastrodin pharmacokinetics in rats},
	journal = {Acta Pharmacologica Sinica},
	volume = {7},
	number = {2},
	year = {2016},
	keywords = {},
	abstract = {Circadian fluctuations of pharmacokinetic parameters of [3H]gastrodin; Maximal time to reach peak (1.12 h) and the maximal absorption rate constant (4 h-1) appeared when [3H]gastrodin (18.5 MBq/kg) was given intragastrically at 08:00 and 20:00. The area under the plasma radioactivity curve (AUC) was found to be lowest (143*103 cpm/ml.h) when [3H]gastrodin was given at 02:00.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/4920}
}