@article{APS4919,
author = {Zheng-wu ZOU},
title = {A simplification in calculating drug concentration in plasma after two consecutive infusions},
journal = {Acta Pharmacologica Sinica},
volume = {7},
number = {2},
year = {2016},
keywords = {},
abstract = {This paper described a simpler formula than that of Wagner in 1974 for calculating plasma concentration in two consecutive infusions. Wagner’s formula was:
C=C(ss)+\{[(K21-alpha)(K0S-alphaX1T)-alphaK21XT2]/alpha (alpha-beta)Vc\}e-alpha(i-T)
My formula is:
C=C(ss)*\{1+[(K10-beta)(e-betaT-e-alphaT)/(alpha-beta)(1-e-betaT)]*e-alphat’\}},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/4919}
}