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Effects of etorphine and electro-acupuncture on electroconvulsive shock in rats

  
@article{APS4884,
	author = {Xiao-ping HE and Xiao-ding CAO},
	title = {Effects of etorphine and electro-acupuncture on electroconvulsive shock in rats},
	journal = {Acta Pharmacologica Sinica},
	volume = {7},
	number = {2},
	year = {2016},
	keywords = {},
	abstract = {Seizures were induced by electroconvulsive shock (ECS) in 75 rats. Etorphine (ip) decreased seizure duration, its ED(50) being 11 microg/kg. Etorphine (icv) facilitated seizures with ED(50) 0.35 microg. These effects of etorphine were in a dose-dependent manner. Electroacupuncture (EA) inhibited partially the seizures; this inhibitory effect was reversed by ip naloxone. These results suggest that EA exerts the anticonvulsive action via endogenous opioid system.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/4884}
}