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Relation between bronchospasmolytic action of sophocarpine and cAMP contents in mesencephalon

   
@article{APS4827,
	author = {Dan-fan YAO and Ying-qu LI and Jian-xin WANG and Cun-ren LIU and Yu CHENG},
	title = {Relation between bronchospasmolytic action of sophocarpine and cAMP contents in mesencephalon},
	journal = {Acta Pharmacologica Sinica},
	volume = {7},
	number = {1},
	year = {2016},
	keywords = {},
	abstract = {The contents of cAMP in midbrain were increased by injecting 4% sophocarine-HBr 0.03 ml/kg into the cistern magna of rabbits, but those in medulla, cerebellum were insigfificantly changed. When sophocarine-HBr was injected im into guinea pigs, the contents of cAMP in lung-bronchial tissues and plasma were insignificantly changed, but those contents were significantly increased by injecting aminophylline im. It is suggested that the bronchospasmolytic effect of sophocarpine-HBr may be due to the increase of cAMP content in midbrain.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/4827}
}