@article{APS4781,
author = {Shou-peng ZHU and Jing-yong ZHAO and Kun-yuan SU and Qi-zhong MO and Guo-lin WANG},
title = {Body retention of 169Yb-citrate and its excretion by 4 chelating agents},
journal = {Acta Pharmacologica Sinica},
volume = {5},
number = {4},
year = {2016},
keywords = {},
abstract = {After iv 169Yb-citrate 20 μCi/kg in rats, there was a selective deposition and a high accumulation of 169Yb in skeleton disclosed by a well-type scintillation counting technique. Excretion of 169Yb-citrate was slow. About 20% was excreted from urine and feces in 72h. Both amino carboxylic type chelating agents diethylenetriaminepentaacetic acid (DTPA) and quinamic acid therapy removed large amount of 169Yb-citrate from the body.Polyphosphoric acid type (propyl aminoethylene diphosphoric acid) and sulfhydryl type chelating agents (penicillamine) showed no significant effect.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/4781}
}