@article{APS4713,
author = {Bao-zhong Xie and Guo-jun Hu and Long-xing Yuan and Hong Wang and Wen-de Jiang},
title = {Effect of the central action of propranolol on coronary circulation in dogs},
journal = {Acta Pharmacologica Sinica},
volume = {6},
number = {1},
year = {2016},
keywords = {},
abstract = {In conscious dogs synchronized EEG pattern was demonstrated after intravenous(iv) or intracerebroventricular(icv) injections of dl-propranolol(dl-p),showing decreases of wave frequency and predominance of high amplitude slow waves. This suggests that dl-p blocked the beta-recetors in CNS. Dextroisomer(d-p),however, lacked such a central effect. In aneasthetized dogs the coronary blood flow was significantly decreased by both iv and icv dl-p, but d-p in neither routes showed significant effects. The possible relation between the central and coronary circulatory effects of dl-p was suggested.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/4713}
}