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Antimalarial activities of 2,4-diamino-6-[(4-chlorobenzyl)-N-methyl-amino] quinazoline and its salts

   
@article{APS4591,
	author = {Zu-rui Dai and Yu-tang Li and Lin Chen and Jian-zhang Gong and Guang-yun Li and Gen-di Chen and De-fu Shen and Zhi-min Xin and Xiu-ping Zhang},
	title = {Antimalarial activities of 2,4-diamino-6-[(4-chlorobenzyl)-N-methyl-amino] quinazoline and its salts},
	journal = {Acta Pharmacologica Sinica},
	volume = {3},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {We synthesized 2,4-diamino- 6-[(4-chlorobenzyl )-N-methylamino]quinazoline (Am-2159) and its salts. Tests were conducted for their activities against both rodent and simian malarial parasites. Am-2159 and its salts showed prophylactic action on Plasmodium yoelii infection in mice (Table 1), yet their effect lasted for },
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/4591}
}