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Multiple mechanisms involved in oxytocin-induced modulation of myometrial contractility

  
@article{APS4005,
	author = {Anatoly Shmygol and Joanna Gullam and Andrew Blanks and Steven Thornton},
	title = {Multiple mechanisms involved in oxytocin-induced modulation of myometrial contractility},
	journal = {Acta Pharmacologica Sinica},
	volume = {27},
	number = {7},
	year = {2016},
	keywords = {},
	abstract = {Oxytocin is a small peptide hormone with multiple sites of action in human body. It regulates a large number of reproduction-related processes in all species. Particularly important is its ability to stimulate uterine contractility. This is achieved by multiple mechanisms involving sarcoplasmic reticulum Ca2+ release and sensitization of the contractile apparatus to Ca2+. In this paper, we review the data published by us and other groups on oxytocin-induced modulation of uterine contractility. We conclude that sensitization of contractile apparatus to Ca2+ is the most relevant physiological effect of oxytocin on human myometrium.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/4005}
}