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SRC-3/AIB1: transcriptional coactivator in oncogenesis

  
@article{APS3993,
	author = {Jun Yan and Sophia Y Tsai and Ming-jer Tsai},
	title = {SRC-3/AIB1: transcriptional coactivator in oncogenesis},
	journal = {Acta Pharmacologica Sinica},
	volume = {27},
	number = {4},
	year = {2016},
	keywords = {},
	abstract = {Steroid receptor coactivator-3 (SRC-3, also known as NCoA3, AIB1, p/CIP, RAC3, ACTR, and TRAM1), localized on a frequently amplified region, 20q12, has been associated with multiple cancers, including breast, gastric and prostate cancers. Although SRC-3 has been implicated as an oncogene, compelling evidence has only recently emerged implicating it as a causal factor in the genesis of human cancers. Here, we summarize recent evidence that indicates aberrant SRC-3 expression is important in hormone-sensitive and -insensitive human cancers.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/3993}
}