Vol 43, No 12 (December 2022): Acta Pharmacologica Sinica

Editorial

APS celebrates the 90th anniversary of SIMM   Pages (3013–3014)
Jia LI

Review Article

Antitumor pharmacological research in the era of personalized medicine   Pages (3015–3020)
Min Huang, Mei-yu Geng, Jian Ding
Structure genomics of SARS-CoV-2 and its Omicron variant: drug design templates for COVID-19   Pages (3021–3033)
Can-rong Wu, Wan-chao Yin, Yi Jiang, H. Eric Xu
MC1R and melanin-based molecular probes for theranostic of melanoma and beyond   Pages (3034–3044)
Hui Shi, Zhen Cheng
Nanosized drug delivery systems modulate the immunosuppressive microenvironment to improve cancer immunotherapy   Pages (3045–3054)
Wen-lu Yan, Tian-qun Lang, Wen-hui Yuan, Qi Yin, Ya-ping Li
Artemisinin derivative SM934 in the treatment of autoimmune and inflammatory diseases: therapeutic effects and molecular mechanisms   Pages (3055–3061)
Xiao Tong, Li Chen, Shi-jun He, Jian-ping Zuo
Chemistry and bioactivity of secondary metabolites from South China Sea marine fauna and flora: recent research advances and perspective   Pages (3062–3079)
Jiao Liu, Yu-cheng Gu, Ming-zhi Su, Yue-wei Guo
Multi-compound and drug-combination pharmacokinetic research on Chinese herbal medicines   Pages (3080–3095)
Chuan Li, Wei-wei Jia, Jun-ling Yang, Chen Cheng, Olajide E. Olaleye
Mass spectrometry imaging: new eyes on natural products for drug research and development   Pages (3096–3111)
Jin-jun Hou, Zi-jia Zhang, Wen-yong Wu, Qing-qing He, Teng-qian Zhang, Ya-wen Liu, Zhao-jun Wang, Lei Gao, Hua-li Long, Min Lei, Wan-ying Wu, De-an Guo
Proteomic characterization of post-translational modifications in drug discovery   Pages (3112–3129)
Lin-hui Zhai, Kai-feng Chen, Bing-bing Hao, Min-jia Tan

Article

Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects   Pages (3130–3138) Open
Hong-jie Qian, Yu Wang, Meng-qi Zhang, Yuan-chao Xie, Qing-qing Wu, Li-yu Liang, Ye Cao, Hua-qing Duan, Guang-hui Tian, Juan Ma, Zhuo-bing Zhang, Ning Li, Jing-ying Jia, Jing Zhang, Haji Akber Aisa, Jing-shan Shen, Chen Yu, Hua-liang Jiang, Wen-hong Zhang, Zhen Wang, Gang-yi Liu
SCN8A epileptic encephalopathy mutations display a gain-of-function phenotype and divergent sensitivity to antiepileptic drugs   Pages (3139–3148)
Qian-bei Guo, Li Zhan, Hai-yan Xu, Zhao-bing Gao, Yue-ming Zheng