Vol 39, No 1 (January 2018) - Acta Pharmacologica Sinica

YL-0919, a dual 5-HT_1A partial agonist and SSRI, produces antidepressant- and anxiolytic-like effects in rats subjected to chronic unpredictable stress Pages (12-23)

Yu-hua RAN, Xiao-xu HU, Yu-lu WANG, Nan ZHAO, Li-ming ZHANG, Hua-xia LIU, Yun-feng LI

Carnosine suppresses oxygen-glucose deprivation/ recovery-induced proliferation and migration of reactive astrocytes of rats in vitro Pages (24-34)

Li OU-YANG, Yuan LIU, Bing-yu WANG, Pei CAO, Jing-jing ZHANG, Yu-yan HUANG, Yao SHEN, Jian-xin LYU

WNK1 is required for proliferation induced by hypotonic challenge in rat vascular smooth muscle cells Pages (35-47)

Ya-juan ZHANG, Hua-qing ZHENG, Bao-yi CHEN, Lu SUN, Ming-ming MA, Guan-lei WANG, Yong-yuan GUAN

Activation of aldehyde dehydrogenase 2 slows down the progression of atherosclerosis via attenuation of ER stress and apoptosis in smooth muscle cells Pages (48-58)

Mei-yan YANG, Ya-bin WANG, Bo HAN, Bo YANG, Yu-wei QIANG, Yan ZHANG, Zhao WANG, Xu HUANG, Jie LIU, Yundai CHEN, Jun REN, Feng CAO, Yong XU

Resveratrol alleviates diabetic cardiomyopathy in rats by improving mitochondrial function through PGC-1α deacetylation Pages (59-73)

Wei-jin FANG, Chun-jiang WANG, Yang HE, Yu-lu ZHOU, Xiang-dong PENG, Shi-kun LIU

Osthole prevents acetaminophen-induced liver injury in mice Pages (74-84)

Yun CAI, Wu SUN, Xin-xin ZHANG, Yan-die LIN, Hao CHEN, Hao LI

Protostemonine effectively attenuates lipopolysaccharide-induced acute lung injury in mice Pages (85-96)

Ya-xian WU, Hui-qiong HE, Yun-juan NIE, Yun-he DING, Lei SUN, Feng QIAN

Kappa-opioid receptor agonist U50448H protects against renal ischemia-reperfusion injury in rats via activating the PI3K/Akt signaling pathway Pages (97-106)

Li-jie LIU, Jian-jun YU, Xiao-lin XU

(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fcγ receptor signaling Pages (107-116)

Qing QI, Heng LI, Ze-min LIN, Xiao-qian YANG, Feng-hua ZHU, Yu-ting LIU, Mei-juan SHAO, Lu-yao ZHANG, Yan-sheng XU, Yu-xi YAN, Lan-lan SUN, Shi-jun HE, Wei TANG, Jian-ping ZUO

A novel and quick PCR-based method to genotype mice with a leptin receptor mutation (db/db mice) Pages (117-123)

Bao-yu PENG, Qiang WANG, Yan-hong LUO, Jian-feng HE, Tao TAN, Hua ZHU

MicroRNA-132 suppresses cell proliferation in human breast cancer by directly targeting FOXA1 Pages (124-131)

Dan WANG, Jin REN, Hui REN, Jin-ling FU, Dan YU

IR-780-loaded polymeric micelles enhance the efficacy of photothermal therapy in treating breast cancer lymphatic metastasis in mice Pages (132-139)

Bin HE, Hai-yan HU, Tao TAN, Hong WANG, Kao-xiang SUN, Ya-ping LI, Zhi-wen ZHANG

Integrated pharmacokinetic/viral dynamic model for daclatasvir/asunaprevir in treatment of patients with genotype 1 chronic hepatitis C Pages (140-153)

He-chuan WANG, Yu-peng REN, Yue QIU, Jenny ZHENG, Gai-ling LI, Chuan-pu HU, Tian-yan ZHOU, Wei LU, Liang LI

Computational insights into the G-protein-biased activation and inactivation mechanisms of the μ opioid receptor Pages (154-164)

Jian-xin CHENG, Tao CHENG, Wei-hua LI, Gui-xia LIU, Wei-liang ZHU, Yun TANG

Vol 39, No 1 (January 2018): Acta Pharmacologica Sinica

Article

YL-0919, a dual 5-HT_1A partial agonist and SSRI, produces antidepressant- and anxiolytic-like effects in rats subjected to chronic unpredictable stress Pages (12-23)

Carnosine suppresses oxygen-glucose deprivation/ recovery-induced proliferation and migration of reactive astrocytes of rats in vitro Pages (24-34)

WNK1 is required for proliferation induced by hypotonic challenge in rat vascular smooth muscle cells Pages (35-47)

Activation of aldehyde dehydrogenase 2 slows down the progression of atherosclerosis via attenuation of ER stress and apoptosis in smooth muscle cells Pages (48-58)

Resveratrol alleviates diabetic cardiomyopathy in rats by improving mitochondrial function through PGC-1α deacetylation Pages (59-73)

Osthole prevents acetaminophen-induced liver injury in mice Pages (74-84)

Protostemonine effectively attenuates lipopolysaccharide-induced acute lung injury in mice Pages (85-96)

Kappa-opioid receptor agonist U50448H protects against renal ischemia-reperfusion injury in rats via activating the PI3K/Akt signaling pathway Pages (97-106)

(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fcγ receptor signaling Pages (107-116)

A novel and quick PCR-based method to genotype mice with a leptin receptor mutation (db/db mice) Pages (117-123)

MicroRNA-132 suppresses cell proliferation in human breast cancer by directly targeting FOXA1 Pages (124-131)

IR-780-loaded polymeric micelles enhance the efficacy of photothermal therapy in treating breast cancer lymphatic metastasis in mice Pages (132-139)

Integrated pharmacokinetic/viral dynamic model for daclatasvir/asunaprevir in treatment of patients with genotype 1 chronic hepatitis C Pages (140-153)

Computational insights into the G-protein-biased activation and inactivation mechanisms of the μ opioid receptor Pages (154-164)

Review Article

Pathogenic roles of microvesicles in diabetic retinopathy Pages (1-11)

Cover Image

Vol 39, No 1 (January 2018): Acta Pharmacologica Sinica

Article

YL-0919, a dual 5-HT1A partial agonist and SSRI, produces antidepressant- and anxiolytic-like effects in rats subjected to chronic unpredictable stress Pages (12-23)

Carnosine suppresses oxygen-glucose deprivation/ recovery-induced proliferation and migration of reactive astrocytes of rats in vitro Pages (24-34)

WNK1 is required for proliferation induced by hypotonic challenge in rat vascular smooth muscle cells Pages (35-47)

Activation of aldehyde dehydrogenase 2 slows down the progression of atherosclerosis via attenuation of ER stress and apoptosis in smooth muscle cells Pages (48-58)

Resveratrol alleviates diabetic cardiomyopathy in rats by improving mitochondrial function through PGC-1α deacetylation Pages (59-73)

Osthole prevents acetaminophen-induced liver injury in mice Pages (74-84)

Protostemonine effectively attenuates lipopolysaccharide-induced acute lung injury in mice Pages (85-96)

Kappa-opioid receptor agonist U50448H protects against renal ischemia-reperfusion injury in rats via activating the PI3K/Akt signaling pathway Pages (97-106)

(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fcγ receptor signaling Pages (107-116)

A novel and quick PCR-based method to genotype mice with a leptin receptor mutation (db/db mice) Pages (117-123)

MicroRNA-132 suppresses cell proliferation in human breast cancer by directly targeting FOXA1 Pages (124-131)

IR-780-loaded polymeric micelles enhance the efficacy of photothermal therapy in treating breast cancer lymphatic metastasis in mice Pages (132-139)

Integrated pharmacokinetic/viral dynamic model for daclatasvir/asunaprevir in treatment of patients with genotype 1 chronic hepatitis C Pages (140-153)

Computational insights into the G-protein-biased activation and inactivation mechanisms of the μ opioid receptor Pages (154-164)

Review Article

Pathogenic roles of microvesicles in diabetic retinopathy Pages (1-11)

Cover Image

YL-0919, a dual 5-HT_1A partial agonist and SSRI, produces antidepressant- and anxiolytic-like effects in rats subjected to chronic unpredictable stress Pages (12-23)