Vol 38, No 5 (May 2017): Acta Pharmacologica Sinica

Reviews

Insights into molecular therapy of glioma: current challenges and next generation blueprint   Pages (591-613)
Y RAJESH, Ipsita PAL, Payel BANIK, Sandipan CHAKRABORTY, Sachin A BORKAR, Goutam DEY, Ahona MUKHERJEE, Mahitosh MANDAL
New knowledge of the mechanisms of sorafenib resistance in liver cancer   Pages (614-622)
Yan-jing ZHU, Bo ZHENG, Hong-yang WANG, Lei CHEN

Original Article

Multichannel polymer scaffold seeded with activated Schwann cells and bone mesenchymal stem cells improves axonal regeneration and functional recovery after rat spinal cord injury   Pages (623–637)
Er-zhu YANG, Guo-wang ZHANG, Jian-guang XU, Shuai CHEN, Hua WANG, Liang-liang CAO, Bo LIANG, Xiao-feng LIAN
Synthesis of the novel PARP-1 inhibitor AG-690/11026014 and its protective effects on angiotensin II-induced mouse cardiac remodeling   Pages (638-650)
Guo-shuai FENG, Cui-ge ZHU, Zhuo-ming LI, Pan-xia WANG, Yi HUANG, Min LIU, Ping HE, Lan-lan LOU, Shao-rui CHEN, Pei-qing LIU
A novel STAT3 inhibitor negatively modulates platelet activation and aggregation   Pages (651-659)
Zhuan XU, Yu-jia XU, Ya-nan HAO, Li-jie REN, Zu-bin ZHANG, Xin XU, Bi-yin CAO, Ke-sheng DAI, Li ZHU, Qi FANG, Yan KONG, Xin-liang MAO
Dicer1/miR-29/HMGCR axis contributes to hepatic free cholesterol accumulation in mouse non-alcoholic steatohepatitis   Pages (660–671)
Ming-xia LIU, Man GAO, Chun-zhu LI, Cun-zhi YU, Hong YAN, Chun PENG, Yu LI, Cheng-gang LI, Ze-long MA, Yang ZHAO, Meng-fan PU, Ling-ling MIAO, Xin-ming QI, Jin REN
15-Deoxy-Δ12,14-prostaglandin J2 alleviates hepatic ischemia-reperfusion injury in mice via inducing antioxidant response and inhibiting apoptosis and autophagy   Pages (672–687)
Kan CHEN, Jing-jing LI, Sai-nan LI, Jiao FENG, Tong LIU, Fan WANG, Wei-qi DAI, Yu-jing XIA, Jie LU, Ying-qun ZHOU, Chuan-yong GUO
Geniposide ameliorates TNBS-induced experimental colitis in rats via reducing inflammatory cytokine release and restoring impaired intestinal barrier function   Pages (688–698)
Bin XU, Yan-li LI, Ming XU, Chang-chun YU, Meng-qiao LIAN, Ze-yao TANG, Chuan-xun LI, Yuan LIN
Sarsasapogenin-AA13 inhibits LPS-induced inflammatory responses in macrophage cells in vitro and relieves dimethylbenzene-induced ear edema in mice   Pages (699–709)
Dong DONG, Nan-nan ZHOU, Rui-xuan LIU, Jia-wei XIONG, Hui PAN, Si-qi SUN, Lei MA, Rui WANG
Preclinical evaluation of the efficacy, pharmacokinetics and immunogenicity of JS-001, a programmed cell death protein-1 (PD-1) monoclonal antibody   Pages (710–718)
Jie FU, Fang WANG, Li-hou DONG, Jing ZHANG, Cheng-lian DENG, Xue-li WANG, Xin-yao XIE, Jing ZHANG, Ruo-xian DENG, Li-bo ZHANG, Hai WU, Hui FENG, Bo CHEN, Hai-feng SONG
Insights into the molecular mechanisms of Polygonum multiflorum Thunb-induced liver injury: a computational systems toxicology approach   Pages (719–732)
Yin-yin WANG, Jie LI, Zeng-rui WU, Bo ZHANG, Hong-bin YANG, Qin WANG, Ying-chun CAI, Gui-xia LIU, Wei-hua LI, Yun TANG

Erratum

Erratum: Dihydromyricetin protects neurons in an MPTP-induced model of Parkinson's disease by suppressing glycogen synthase kinase-3 beta activity   Pages (733)
Acta Pharmacol Sin
Erratum: Geniposide ameliorates TNBS-induced experimental colitis in rats via reducing inflammatory cytokine release and restoring impaired intestinal barrier function   Pages (734)
Acta Pharmacol Sin