Vol 36, No 9 (September 2015): Acta Pharmacologica Sinica

Review

Landmark studies on the glucagon subfamily of GPCRs: from small molecule modulators to a crystal structure   Pages (1033-1042) Open
De-hua Yang, Cai-hong Zhou, Qing Liu, Ming-wei Wang

Original Article

Protease Omi cleaving Hax-1 protein contributes to OGD/R-induced mitochondrial damage in neuroblastoma N2a cells and cerebral injury in MCAO mice   Pages (1043-1052)
Jia-yuan Wu, Mei Li, Li-juan Cao, Mei-ling Sun, Dong Chen, Hai-gang Ren, Qin Xia, Zhou-teng Tao, Zheng-hong Qin, Qing-song Hu, Guang-hui Wang
WSS25, a sulfated polysaccharide, inhibits RANKL-induced mouse osteoclast formation by blocking SMAD/ID1 signaling   Pages (1053-1064)
Cheng Chen, Yi Qin, Jian-ping Fang, Xin-yan Ni, Jian Yao, Hai-ying Wang, Kan Ding
Physical performance and life quality in postmenopausal women supplemented with vitamin D: a two-year prospective study   Pages (1065-1073)
Li-hong Gao, Wen-jun Zhu, Yu-juan Liu, Jie-mei Gu, Zhen-lin Zhang, Ou Wang, Xiao-ping Xing, Ling Xu
New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway   Pages (1074-1084)
Kang Chen, Bi-zhu Chu, Feng Liu, Bin Li, Chun-mei Gao, Lu-lu Li, Qin-sheng Sun, Zhi-fa Shen, Yu-yang Jiang
Synergistic suppression of human breast cancer cells by combination of plumbagin and zoledronic acid In vitro   Pages (1085-1098)
Han Qiao, Ting-yu Wang, Wei Yan, An Qin, Qi-ming Fan, Xiu-guo Han, Yu-gang Wang, Ting-ting Tang
JNK is required for maintaining the tumor-initiating cell-like properties of acquired chemoresistant human cancer cells   Pages (1099-1106)
Yuan Liu, Xia Zhang, Juan Wang, Jun Yang, Wen-fu Tan
LKB1 gene inactivation does not sensitize non-small cell lung cancer cells to mTOR inhibitors in vitro   Pages (1107-1112)
Ping Xiao, Lin-lin Sun, Jing Wang, Rui-li Han, Qing Ma, Dian-sheng Zhong
Cathepsin L suppression increases the radiosensitivity of human glioma U251 cells via G2/M cell cycle arrest and DNA damage   Pages (1113-1125)
Qing-qing Zhang, Wen-juan Wang, Jun Li, Neng Yang, Gang Chen, Zhong Wang
Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells   Pages (1126-1136)
Deng-wei Wu, Fei Mao, Yan Ye, Jian Li, Chuan-lian Xu, Xiao-min Luo, Jing Chen, Xu Shen
Discovery and structural optimization of 1-phenyl-3-(1-phenylethyl)urea derivatives as novel inhibitors of CRAC channel   Pages (1137-1144)
Hai-zhen Zhang, Xiao-lan Xu, Hua-yan Chen, Sher Ali, Dan Wang, Jun-wei Yu, Tao Xu, Fa-jun Nan
Structural basis for 18-β-glycyrrhetinic acid as a novel non-GSH analog glyoxalase I inhibitor   Pages (1145-1150)
Hong Zhang, Qiang Huang, Jing Zhai, Yi-ning Zhao, Li-ping Zhang, Yun-yun Chen, Ren-wei Zhang, Qing Li, Xiao-peng Hu
Enhancement of cellular uptake, transport and oral absorption of protease inhibitor saquinavir by nanocrystal formulation   Pages (1151-1160)
Yuan He, Deng-ning Xia, Qiu-xia Li, Jin-song Tao, Yong Gan, Chi Wang